When it comes to disorders of the older brain, Alzheimer’s disease is a biggie, and it has a pretty clear early warning sign. “The area of the brain Alzheimer’s affects most is short-term memory,” says Dr. Wasserman. “So the major early symptom of the disease is short-term memory loss—that’s what everyone notices.”
This could include everything from forgetting the day’s events to an inability to recall instructions. Repeating questions or forgetting recent conversations are also among the indicators, says David M. Holtzman, MD, Professor and Chairman, Department of Neurology, Washington University in St. Louis.
“This can be caused by dysfunction in the medial temporal lobe, frequently among the first signs of Alzheimer’s disease as well as some other brain disorders,” he explains.
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