St. John’s Wort
Sometimes used to help people with depression, this herbal remedy isn’t a proven treatment for that or any other health condition. It can make your liver release enzymes (things that boost certain chemical reactions in your body) that can weaken some medications. Those include cholesterol drugs like lovastatin (Altoprev and Mevacor), the erectile dysfunction drug sildenafil (Viagra), and digoxin (Lanoxin), used to treat certain heart conditions.