1. Spoon nails (or koilonychia), a phenomenon when your nails look like a spoon with raised ridges and a scooped out depression, may be a sign of hemochromatosis, a disorder that occurs when your body produces too much iron. They’re also associated with iron-deficiency anemia, heart disease, and poor blood circulation.
2. Nail clubbing appears when your fingertips become enlarged and your nails become curved downward. This kind of nail growth can be a sign of low oxygen in your blood that is usually caused by lung disease. Clubbing can also be related to liver or kidney disease, heart problems, inflammatory bowel disease, and AIDS.
3. Nails that are detached from their beds usually indicate hyperthyroidism, a condition when your thyroid gland is releasing too many hormones into your body. Loose nails can also signify a fungal infection, psoriasis, poor blood circulation or amyloidosis, or an excess amount of the protein amyloid in your organs and tissues.