20 Important Things Doctors Wish You Knew About Arthritis

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13. You should try multiple inhibitors

Tumor necrosis factor (TNF) is an inflammatory protein responsible for pain and cartilage degeneration in RA, and drugs called TNF inhibitors can sometimes block it. And if one TNF inhibitor—such as etanercept (Enbrel) or adalimumab (Humira)—doesn’t work, try another.

In a recent study, 43 percent of patients who didn’t respond to one type of TNF inhibitor responded positively to a different one. So, talk to your doctor about trying one TNF inhibitor (or two).

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