Paget’s disease
Paget’s disease is a relatively slow-progressing condition in which the bones fail to grow properly—a sufferer’s bones become large, weak, and misshapen. The disease tends to affect the spine, skull, pelvis, and extremities, says Dr. Goitz. Paget’s disease rarely spreads from one site to another.
For example, if the disease targets the pelvis, the spine or skull will escape harm. Although Paget’s generally runs its course and disappears, any bone damage will be irreversible; the condition can cause pain, stiffness, fractures, and other problems if not treated properly. Bisphosphonates, which help slow down the process of bone turnover, are the most routine drug treatment for Paget’s.
