10 Unusual Skin Problems That Could Be a Sign of a Serious Disease

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You have a weird rash, part II

Starting a new medication always comes with potential reactions. One serious problem: an allergy called “drug reaction with eosinophilia and systemic symptoms” or DRESS syndrome, a potentially life-threatening condition marked by an inflammation of the liver, heart, and lungs, says dermatologist Cindy Owen in a press release from the American Academy of Dermatology.

Even more confusing: This rash can appear two to eight weeks after starting the med. Watch out if you have a rash accompanied by fever or swelling of lymph nodes.

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