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9 Unexpected Medical Reasons Why You Can’t Sleep

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5. Stimulant medications

As you probably know, many medications can cause difficulty falling asleep, Dr. Howell says. The most common ones include steroids such as prednisone; antidepressants such as bupropion and venlafaxine; stimulants such as methylphenidate and modafinil, adrenal, thyroid replacement medications, beta-agonists and theophylline used for asthma.

Also, some over-the-counter medications, such as some pain medications, allergy, and cold medications, and weight-loss products are packed with caffeine and other stimulants that can disrupt your sleep, according to the Mayo Clinic.

However, if you can’t sleep, Dr. Howell recommends you talk to your doctor about your medication and consider if the benefits you are getting from your medication outweigh the consequences of poor sleep.

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