If you have dry skin—especially in the winter months—you may bet used to feeling itchy. But when a good moisturizer provides no relief, it could be something more serious than dry skin. Itchiness can be caused by some cancers like leukemia and lymphoma, as well as liver disease and kidney failure.
If itching is all over your body, is severe, comes out of nowhere, or is so bad you’re losing sleep because you’re so uncomfortable, talk to your doctor, says Dr. Reynolds. Itchiness with night sweats, fevers, and unexplained weight loss are other red flag symptoms, she says.